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2024 Workshop Programme

Integrative & Personalised Medicine

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The hydroethanolic extract from Arnicae flos demonstrated potent anti-inflammatory properties in vitro and in vivo

08 Jun 2024
Rutherford
Herbal Medicine

Traditionally Arnica montana L. is indicated for treatment of blunt injuries like strains, bruises and contusions that are physiologically accompanied by local inflammation and edema, including activation of the NF-kB pathway and the release of pro-inflammatory prostaglandins and leukotrienes that are produced by cyclooxygenase-2 (COX-2) and 5-lipoxygenase (5-LO). Arnica flowers (A. flos) contain compounds, e.g. sesquiterpene lactones like helenalin or dihydrohelenalin that are known anti-inflammatory compounds. Here we aimed to evaluate the anti-inflammatory efficacy of a hydroethanolic extract from A. flos.

 

Speakers
Johann Röhrl, Senior Manager Preclinical Development

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